|Title||25 Years of the WHO Essential Medicines List: Progress and Challenges|
|Authors||Laing, R., Waning, B., Gray, A., Ford, N., Hoen, E.|
|Journal Name (if applicable)||Lancet|
|Open Access Y/N||Yes|
|Hard copy PDF Available Y/N||yes|
|Abstract||The first WHO essential drugs list, published in 1977, was described as a peaceful revolution in international public health.
The list helped to establish the principle that some medicines were more useful than others and that essential medicines
were often inaccessible to many populations. Since then, the essential medicines list (EML) has increased in size; defining
an essential medicine has moved from an experience to an evidence-based process, including criteria such as publichealth
relevance, efficacy, safety, and cost-effectiveness. High priced medicines such as antiretrovirals are now included.
Differences exist between the WHO model EML and national EMLs since countries face varying challenges relating to
costs, drug effectiveness, morbidity patterns, and rationality of prescribing. Ensuring equitable access to and rational use
of essential medicines has been promoted through WHO’s revised drug strategy. This approach has required an
engagement by WHO on issues such as the effect of international trade agreements on access to essential medicines and
research and development to ensure availability of new essential medicines.